Archive for December, 2008

Internal Medicine News - Rimonabant cut Hb[A.sub.1c] in type 2 diabetic patients

Sunday, December 28th, 2008

New data on rimonabant suggest that the selective endocannabinoid type 1-receptor blocker has beneficial effects on glycemic control and other risk factors in diabetic patients.
In treatment-naive patients with type 2 diabetes, 6 months of rimonabant t…

Chain Drug Review - Application withdrawn

Saturday, December 27th, 2008

Sanofi-aventis has withdrawn its application to sell rimonabant, an antiobesity drug. The decision came after a Food and Drug Administration panel recommended that the agency not approve the drug because of concerns that its use could lead to depression and suicidal thinking.

Related Results

Lancet, BMJ studies sound concern over anti-obesity drug rimonabantRimonabant improves cardiovascular risk profileRimonabant improves cardiovascular r…

Internal Medicine News - Rimonabant enhanced weight loss success, improved lipids

Friday, December 26th, 2008

Rimonabant, an investigational drug that is a cannabinoid-1 receptor blocker, promoted modest but sustained decreases in weight and waist circumference when combined with a low-calorie diet, reported Dr. F. Xavier Pi-Sunyer of the Obesity Research Center at St. Luke’s-Roosevelt Hospital, New …

HealthDay - Weight-Loss Drug Fights Alcoholic Fatty Liver Disease

Monday, December 22nd, 2008

Mice given the weight-loss drug rimonabant became resistant to alcohol’s fat-building effects in the liver, which suggests the medication may help fight alcoholic fatty liver in humans, says a U.S. study.
Alcoholism is the leading cause of liver disease in Western societies, according to background information in the study.
Rimonabant, which blocks cannabinoid receptors, is approved for weight loss in several European countries but ha…

Pharma Marketletter - Sanofi-Aventis’ Acomplia provides long-term cardiovascular benefits; two-year study.

Friday, December 19th, 2008

New findings reported at the American Heart Association Scientific Sessions in New Orleans, Louisiana, show that first-year improvements in cardiovascular risk factors seen in obese patients treated with Sanofi-Aventis’ Acomplia (rimonabant) are sustained in the second year of therapy.

Related Re…

Rimonabant Acomplia: Magical Tool to Fight Monstrous Obesity

Monday, December 15th, 2008

Monster can be defeated only with the help of proper weapon. Obesity is a dangerous monster which is devouring people’s health and their lives. The devil never comes alone; then how can obesity come alone? High blood pressure, high blood sugar, kidney failure, heart attack, arthritis are the killers…

PR Newswire Europe - Acomplia(R) (Rimonabant) Recommended for Approval in the European Union.

Thursday, December 11th, 2008

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> PARIS, France, April 28 /PRNewswire/ — Sanofi-aventis announced today that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Age…

PR Newswire Europe - Long-Term Benefits of Rimonabant Confirmed in Two-Year Study.

Wednesday, December 10th, 2008

NEW ORLEANS, November 9 /PRNewswire/ —
- Results From Rio-North America Trial Show That First Year Improvements in Cardiovascular Risk Factors Maintained in the Second Year of Treatment

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AFP - Sanofi withdraws anti-obesity drug in US

Sunday, December 7th, 2008

PARIS (AFP) — French pharmaceutical group Sanofi-Aventis said Friday it had withdrawn an application for regulatory approval for its anti-obesity drug Acomplia in the United States.
A panel of experts from the US Food and Drug Administration concluded ear…

8 1/2 Pounds Lost in 16 Weeks With New Drug

Wednesday, December 3rd, 2008

June 17, 2004 — A new drug helped obese people drop up to 8.5 pounds over 16 weeks, researchers report.

Its planned brand name — pending FDA approval — is Acomplia. For now, it’s still going by its generic name rimonabant. But it already has a nickname: the munchies drug. That’s because it works like marijuana in reverse. It blocks cannabinoid receptors in the brain.

Rimonabant curbs appetite. It also cuts the urge to s…